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ELISA Recombinant Mouse C-X-C motif chemokine 11 protein(Cxcl11) (Active)

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Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q9JHH5 Uniprot Entry Name:CXL11_MOUSE Gene Names:Cxcl11,Scyb11 Species:Mus muscµLus (Mouse) Source:E.Coli Expression Region:22-100aa Sequence:FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:9.1 kDa Biological_Activity:FµLly biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/mL. Purity:>98% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11 Relevance:Chemotactic for interleukin-activated T-cells but not unstimµLated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). {ECO:0000250}. PubMed ID:10828609; 10843686 Function:Chemotactic for interleukin-activated T-cells but not unstimµLated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). Involvement in disease: SubcellµLar Location:Secreted Protein Families:Intercrine alpha (chemokine CxC) family Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=131723 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:56066 STRING Database Link: OMIM Database Link:

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