ELISA gag Antibody, FITC

Quantity :50µg Clone Number: Aliases:gag antibody; Gag polyprotein antibody; Pr65gag antibody; Core polyprotein) [Cleaved into: Matrix protein p15 antibody; MA); RNA-binding phosphoprotein p12 antibody; pp12); Capsid protein p30 antibody; CA); Nucleocapsid protein p10-Gag antibody; NC-gag)] antibody Product Type:Polyclonal Antibody Immunogen Species:Moloney murine leukemia virus UniProt ID:P03332 Immunogen:Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA) Raised in:Rabbit Reactivity:Moloney murine leukemia virus Tested Applications: Background:Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjµgate ubiquitin molecµLes to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a mµLtipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsµLates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCµg elements within the packaging signal, located near the 5\\\'-end of the genome. This binding is dependent on genome dimerization. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:gag Research Areas:Others